NASA Shuttle Launch of the Space Shuttle Endeavor on February 8, 2010. Scheduled to be the last night time shuttle launch by NASA.
Viewed and filmed from Brevard Landing boat launch looking across Mosquito Lagoon to the Kennedy Space Center. Brevard Landing puts you about 10 miles away from the shuttle launch pad. We could even hear the Kennedy Space Center countdown across the Lagoon.
This is an easy area to access from the Disney World/Orlando area by just taking the 528 toll road over to the east coast. From there, you can go up I-95 to various exits providing access to the beach and intracoastal waterway, providing many places to watch the launches.
After this one, there's only four left, so check the NASA launch schedule and see if it coincides with your Disney World vacation. Maybe you can catch one of the last four!